2015-2016 미국 University of California, San Francisco, 방문교수
2009- 현재 성균관대학교 융합생명공학과 교수
학술지 논문
(2020)
Gamma secretase inhibition impairs HCMV replication by reduction of immediate early gene expression at the transcriptional level.
ANTIVIRAL RESEARCH.
183,
(2020)
Yes-Associated Protein Enhances Fibroblast Growth Factor 2-Dependent Neural Stem Cell Proliferation by Induction of Fibroblast Growth Factor Receptor Expression.
STEM CELLS AND DEVELOPMENT.
29,
18
(2020)
The Neocortical Progenitor Specification Program Is Established through Combined Modulation of SHH and FGF Signaling.
JOURNAL OF NEUROSCIENCE.
40,
36
(2020)
Non-cell autonomous promotion of astrogenesis at late embryonic stages by constitutive YAP activation.
SCIENTIFIC REPORTS.
10,
1
(2020)
Protein Arginine Methyltransferase 1 (PRMT1) Selective Inhibitor, TC-E 5003, Has Anti-Inflammatory Properties in TLR4 Signaling.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.
21,
9
(2020)
Identification of a novel triterpene saponin from Panax ginseng seeds, pseudoginsenoside RT8, and its antiinflammatory activity.
JOURNAL OF GINSENG RESEARCH.
44,
1
(2019)
AKT1-targeted proapoptotic activity of compound K in human breast cancer cells.
JOURNAL OF GINSENG RESEARCH.
43,
4
(2019)
PACT increases mammalian embryonic neural stem cell properties by facilitating activation of the notch signaling pathway.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.
513,
2
(2019)
Cigarette smoke extracts and cadmium induce COX-2 expression through gamma-secretase-mediated p38 MAPK activation in C6 astroglia cells.
PLOS ONE.
14,
2
(2018)
Ttyh1 regulates embryonic neural stem cell properties by enhancing the Notch signaling pathway.
EMBO REPORTS.
19,
11
(2018)
Photoaging protective effects of BIOGF1K, a compound-K-rich fraction prepared from Panax ginseng.
JOURNAL OF GINSENG RESEARCH.
42,
1
(2017)
VEGFR2 alteration in Alzheimer's disease.
SCIENTIFIC REPORTS.
7,
(2017)
Human Cytomegalovirus IE2 Protein Disturbs Brain Development by the Dysregulation of Neural Stem Cell Maintenance and the Polarization of Migrating Neurons.
JOURNAL OF VIROLOGY.
91,
17
(2017)
Nuclear factor kappa-B-and activator protein-1-mediated immunostimulatory activity of compound K in monocytes and macrophages.
JOURNAL OF GINSENG RESEARCH.
41,
3
(2017)
The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina.
CELL REPORTS.
19,
2
(2017)
TRBP maintains mammalian embryonic neural stem cell properties by acting as a novel transcriptional coactivator of the Notch signaling pathway.
DEVELOPMENT.
144,
5
(2017)
Neprilysin facilitates adipogenesis through potentiation of the phosphatidylinositol 3-kinase (PI3K) signaling pathway.
MOLECULAR AND CELLULAR BIOCHEMISTRY.
430,
1-2
(2016)
Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors.
Journal of Developmental Biology.
4,
29
(2015)
Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis.
CELL REPORTS.
12,
12
(2015)
NF-kappa B signaling regulates the generation of intermediate progenitors in the developing neocortex.
GENES TO CELLS.
20,
9
특허/프로그램
COMPOSITION FOR INHIBITING HUMAN CYTOMEGALOVIRUS REPLICATION.
15/013,510.
20171024.
미국
METHOD FOR TREATING GLIOMA USING TARBP2 EXPRESSION INHIBITOR.
14/558,961.
20170214.
미국
HCMV 바이러스 복제 억제용 조성물(COMPOSITION FOR HCMV VIRUS REPLICATION INHIBITION).
10-2015-0017213.
20151125.
대한민국
목적 유전자의 신경세포 타입-특이적 발현 방법 및 이를 이용한 동물 모델(Methods for Neural Cell-Type Specific Expression of Target Gene and Animal Models Using the Same).
10-1290799-0000.
20130723.
대한민국
초음파 영상 기반의 유전자 전달 기술을 이용한 형질전환 동물의 제조방법(The method for producing transgenic animals using ultrasound image-guided gene delivery technique).
10-1257002-0000.
20130416.
대한민국
초음파 영상 기반의 유전자 전달 기술 및 아데노바이러스 벡터를 이용한 형질전환 동물의 제조방법(The method for producing transgenic animals using ultrasound image-guided gene delivery technique and adenovirus vector).
10-1250991-0000.
20130329.
대한민국
초음파 영상 기반의 유전자 전달 기술 및 리포터 유전자를 이용한 생체 내 영상에 의한 형질전환 동물의 선별 방법(The method for screening transgenic animals generated by ultrasound image-guided gene delivery technique using in vivo imaging of reporter gene expression).
10-1242114-0000.
20130305.
대한민국
학술회의논문
(2019)
Pact Facilitates Activation of the Notch Signaling Pathway by Strengthening the Association between Cbf1 and Notch Intracellular Domain.
2019 ASCB|EMBO Meeting.
미국
(2016)
Neprilysin facilitates adipogenesis through potentiation of the PI3K signaling pathway.
2016 American Society for Cell Biology Meeting.
미국
(2016)
CCP1 is a positive regulator of Notch signaling pathway in the regulation of neural stem cells.
2016 Society for Neuroscience Annual Meeting.
미국
(2016)
TRBP maintains mammalian embryonic neural stem cell properties by enhancing the Notch signaling pathway.
The 19th Korean Society for Brain and Neural Science Annual Meeting.
대한민국
(2015)
Dual function of suppressor-of-fused in cortical progenitors during mammalian corticogenesis.
2015 Society for Neuroscience Annual Meeting.
미국
(2013)
Upregulation of canonical Notch signaling pathway by an RBP-Jκ-interacting protein.
2013 Society for Neuroscience Annual Meeting.
미국
(2013)
Upregulation of Notch Signaling Pathway by a Novel CBF1-Interacting Protein.
Annual Meeting of the Society for Neuroscience.
미국
(2013)
Role of Tead2 in mammalian brain development.
제 16차 한국뇌신경과학회 학술대회.
대한민국
(2013)
Upregulation of Notch Signaling Pathway by an RBP-J𝜿-Interacting Protein.
제 16차 한국뇌신경과학회 학술대회.
대한민국
(2013)
Upregulation of Notch Signaling Pathway by a Novel CBF1-Interacting Protein.
FENS Featured Regional Meeting.
체코
(2011)
Effect of a novel CBF1-interacting protein on Notch-induced transcriptional activation.
2011 핚국뇌신경과학회 및 MCCS-Asia 학술대회.
대한민국
(2011)
Identification of a Notch signalling modulator1 involved in Notch signalling pathway.
2011 핚국뇌신경과학회 및 MCCS-Asia 학술대회.
대한민국
